Human Rhinovirus Group C Infection in children with Lower Respiratory Tract Infection

Zichun XIANG, Richard GONZALEZ, Zhengde XIE, Yan XIAO, Lan CHEN, Yongjun LI, Chunyan LIU, Yinghui HU, Yuan YAO, Suyun QIAN, Rong GENG, Guy VERNET, Gláucia PARANHOS-BACCALA, Kunling SHEN, Qi Jin, Jianwei WANG

Emerg Infect Dis. 2008 Oct;14(10):1665-7


Human rhinoviruses (HRVs), members of the family Picornaviridae, were fi rst isolated in 1956 (1); to date, >100 serotypes have been identifi ed on the basis of nucleotide sequence homologies. HRVs were previously divided into 2 genetic groups, HRV-A (n = 75) and HRV-B (n = 25). Recently, a putative new and distinct rhinovirus group, HRV-C, has been reportedly found in some patients with respiratory tract infections (RTIs) (2–8). To extend these initial fi ndings and assess the pathogenicity of HRV-C, we investigated its prevalence as well as its clinical and molecular features in children with lower acute RTIs in Beijing, People’s Republic of China.

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