A network in action

We organize a wealth of activities to enhance the scientific capacities of local laboratories in developing countries.

Our initiatives are focused on three key areas: research, technology transfer and training programs, including e-learning. We also publish scientific communications, put out a GABRIEL community newsletter, and organize meetings of network members on a regular basis.

Approach

To foster capacity-building, we seek to:

  • Help developing countries build capacities to ensure laboratory-based surveillance of infectious diseases;
  • Build synergies and create opportunities so that network members can share research approaches and results;
  • Combine local and global perspectives in the design our research programs;
  • Encourage participating laboratories to determine the most relevant priorities for their region.

Initiatives

In Africa, the Americas , Asia and Europe, members of the network carry out surveillance and conduct research projects that target local infectious disease with a major impact on public health.

Collaborative Research

Acute respiratory infections

  • Multicenter Pneumonia study in children under 5 (10 sites)
  • Biomarkers for differentiation between pneumonia/malaria fever in children – Madagascar
  • Active surveillance of severe influenza in Brazil
  • Respiratory Infectious Disease surveillance in Laos
  • Pneumococcal typing for vaccine introduction in Cambodia
  • Etiology of severe pneumonia among Syrian refugees in Lebanon
  • Development and evaluation of a RT PCR for S. pneumoniae typing

Foodborne & Waterborne diseases

  • Evaluation of PCR for Typhoid Diagnostic in Bangladesh, Burkina Faso, Malawi, Ghana
  • Sequence-based rapid identification of enteric pathogens – antibiotic susceptibility study

Tuberculosis

  • National TB survey in & Molecular typing of circulating TB in Lao PDR
  • Inmates Transmission studies in Bangladesh
  • Household transmission studies in Georgia
  • TB MIRU-VNTR typing and implementation of Line Probe Assay for AMR surveillance

Technology Transfer

  • Response to outbreaks: H5N1, MERS-CoV, H7N9
  • Respiratory pathogen molecular test (19 viruses & 5 bacteria)
  • S. pneumoniae and meningitis typing
  • Bacterial molecular test for blood samples
  • Molecular test for typhoid diagnostics

Training and Knowledge-Sharing

Workshops and training programs

  • Molecular biology
  • Immunology
  • Bioinformatics
  • Epidemiology
  • Biosafety/Biosecurity
  • Quality assurance

Quality assurance & biosafety

To address essential challenges in clinical biology and research, we support:

  • Audits, GCLP, SOP, EQA
  • Accredited laboratories
  • Labs moving toward accreditation

GABRIEL network charter

The network follows the principles set out in our charter.
Download Charter PDF

Key figures: ongoing projects

  • 150+ scientists trained on new diagnostic tools
  • 50+ workshops organized
  • 600+ scientists trained in molecular biology, immunology, bioinformatics, epidemiology, biosafety/biosecurity, quality assurance, etc.
  • 10 e-learning modules on epidemiology, clinical research, molecular biology, Zika diagnostics, biobanking
  • 350 publications from 2012 to present